Schwann cell biocompatibility of polycaprolactone/chitosan electrospun scaffolds

Characterization of electrospun nanocomposite scaffolds and biocompatibility with adipose-derived human mesenchymal stem cells

Electrospun nanocomposite scaffolds were fabricated by encapsulating multi-walled carbon nanotubes (MWNT) in poly (lactic acid) (PLA) nanofibers. Scanning electron microscopy (SEM) confirmed the fabrication of nanofibers, and transmission electron microscopy identified the alignment and dispersion of MWNT along the axis of the fibers. Tensile testing showed an increase in the tensile modulus fo...

Fabrication and Biocompatibility of Electrospun Silk Biocomposites

Silk fibroin has attracted great interest in tissue engineering because of its outstanding biocompatibility, biodegradability and minimal inflammatory reaction. In this study, two kinds of biocomposites based on regenerated silk fibroin are fabricated by electrospinning and post-treatment processes, respectively. Firstly, regenerated silk fibroin/tetramethoxysilane (TMOS) hybrid nanofibers with...

Biocompatibility and degradation of tendon-derived scaffolds

Decellularized extracellular matrix has often been used as a biomaterial for tissue engineering applications. Its function, once implanted can be crucial to determining whether a tissue engineered construct will be successful, both in terms of how the material breaks down, and how the body reacts to the material's presence in the first place. Collagen is one of the primary components of extrace...

Electrospun Scaffolds for Heart Valve Tissue Engineering

INTRODUCTION Heart valve replacements are required for a number of heart diseases and replacements, as well as for both pediatric and adult populations. It is estimated that 2.5% of the population has valvular heart disease [1], and annually, over 250,000 people worldwide receive heart valve replacements [1]. Tissue engineering (TE) strategies hold the most promise for permanently restoring the...

Multifunctional Ternary Drug-Loaded Electrospun Scaffolds